Paradoxical prolactin

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منابع مشابه

Paradoxical prolactin response to growth hormone-releasing hormone in a patient with hyperprolactinemia and empty sella.

In a 30-year-old woman with amenorrhea due to hyperprolactinemia, serum PRL increased to twice the basal amount in response to growth hormone-releasing hormone (GHRH). Roentgenological studies revealed no pituitary adenoma but empty sella. Bromocriptine therapy normalized serum PRL and made the paradoxical response to GHRH disappear. The paradoxical response did not occur in any of eight other ...

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Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay.

Based on the assumption that the prolactin receptor (PRLR) is activated by PRL-induced sequential dimerization, potential human PRL (hPRL) antagonists were designed that sterically interfere with binding site 2. We previously reported the unexpected agonistic properties of these hPRL analogs in the rat Nb2 bioassay (Goffin, V., Struman, I., Mainfroid, V., Kinet, S., and Martial, J. A. (1994) J....

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Caffeine attenuates paradoxical sleep deprivation induced- memory impairment during paradoxical sleep windows in rats

There is considerable evidence to support the hypothesis of relationship between paradoxical sleep (PS) and learning–memory processing. It has been suggested that PS is important in memory retention at the specific time course called PS windows (PSW). The time of PSWs occurrence and duration of these PSWs following the training sessions and, the neurochemical nature of PSWs has not been well kn...

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Caffeine attenuates paradoxical sleep deprivation induced- memory impairment during paradoxical sleep windows in rats

There is considerable evidence to support the hypothesis of relationship between paradoxical sleep (PS) and learning–memory processing. It has been suggested that PS is important in memory retention at the specific time course called PS windows (PSW). The time of PSWs occurrence and duration of these PSWs following the training sessions and, the neurochemical nature of PSWs has not been well kn...

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Paradoxical embolism

RATIONALE Paradoxical embolism (PDE) refers to direct passage of venous thrombi into the arterial circulation through an arteriovenous shunt. PATIENT CONCERNS Case 1 presented with initial symptoms of shock and cerebral infarction. Case 2 developed middle cerebral artery occlusion during angiography. DIAGNOSES 2 cases were diagnosed as PDE. INTERVENTIONS They received thrombolytic therapy...

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ژورنال

عنوان ژورنال: Nature

سال: 1980

ISSN: 0028-0836,1476-4687

DOI: 10.1038/284212a0